Herein, O-PKP was indicated for patients with L4 or L5 OVCF. Compared with the T-PKP patients, the O-PKP patients showed shorter operative time and fluoroscopy times (P 0.05), improved VAS and ODI scores at the final follow-up (P 0.05), comparable anteroposterior bone cement distribution, enhanced bilateral bone cement distribution (P < 0.05), and larger sagittal and transverse angles (P < 0.05). Only two T-PKP patients experienced intervertebral disc space leakage. No serious postoperative complications were observed in any of the participants. Between September 2019 and December 2020, we compared the clinical and radiographic outcomes in 31 cases (36 vertebrae) using the “O” entry point PKP intervention (O-PKP) and 31 cases (37 vertebrae) using transverse the process-pedicle approach PKP intervention (T-PKP). This study introduced a novel point “O” puncture approach for percutaneous kyphoplasty (PKP) in patients with L4 or L5 osteoporotic vertebral compression fracture (OVCF) and evaluated its clinical and radiographic outcomes.
